Kuba, what doses do you typically take for your own t4/t3 replacement? I’m on both as well year round, just want to compare cause I feel I’m taking too much atm.

Can you explain what doses and how you take them (all at once vs splitting etc) thank you in advance

Jordan are you still on thyroid replacement t4+t3 or did you drop those when you decided to go back to trt+?

Free thyroxine IS free t4 so its included in the test. Ft3 above the reference range means your tiromel is legit.

TSH around 2 just shows that your thyroid meds are not fully suppressing your Pituitary-thyroid signaling, which is okay.

if you aint got a thyroid problem (hashimotos etc) to begin with, you could drop t3.

Otherwise i´d…

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IMo theres nothing wrong with adding in a low dose of t3, like 5mcg morning + 5mcg afternoon to get your ft3 up. Thyroid replacement with only t4 usually leads to high normal ft4 levels with lower ft3 levels. Most of patients feel fine with that, but a ft3 that low could lead to a slower metabolism than you want it to be

Thyroid replacement is usually just t4, or t4+t3arely t3 on its own. Get bloods done after you came off t3 for a month, you likely gonna need thyroid hormone replacement if you your metabolism was sluggish before starting t3. Your GP or endo is gonna base that on TSH, if you find a good one, he will treat you by your ft4 and ft3 numbers…

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T4 is low af on your bloodwork, t4 is the standard of care in thyroid replacement, ft3 highly fluctuates depending on various circumstances. In your case I’d just do t4, starting with 150mcg as 100mcg doesn’t even seem to bring your ft4 into the reference range. I suggested reading the thyroid replacement articles on hormonesdemystified.com

Ive had comparable issues when i wa susing too much t3 and not enougt t4. The t3:t4 ratio in NDT is 1:4, the human t3:t4 ratio in healthy individuals is usually between 1:10-20 t3 to t4. NDT is derived from pigs and has an unphysiological high amount of t3, which shows as well in your blood work (high ft3, low ft4).

If you use to take all of…

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Then it’s pretty sure your t3 is bunk. You should’ve gotten free t4 too btw.

at what time of the day did you draw bloods and how many hours before did you take the t3 tab? Do you split dose the t3 or all at once?

TSH of 6.73 is high af, and im pretty sure the increase from 112 to 125mcg t4 wont cut it. Id do blood again before doing a cycle, being hypo on cycle will just lead to more fat gain. Decreasing your dose to put on mass will result in just adding fat instead of muscle with increased calories

var, tbol, low test (<150mg), primo.. depends on the sides you wanna avaoid except acne

Nobody wants to zero his or her ft4 lol. I think using combination therapy (t4+t3) is the future of hypothyroidism treatment and in a few years, mainstream medicine will recognize it’s better outcomes

I know. I just wonder that bodybuilders often use t4+t3 together, despite the standard of care hypothyroidism management is t4 only regarding to the American and European thyroid associations.

Ty. I notice a trend towards using t3 to grow in pro bodybuilding recently. I’ve read some articles of Taeian Clark where he states some studies about androgen receptor upregulation from t3, quiet interesting imo.

Dawid did you continue to use 1tab novothyral+ 50mcg t4 for this whole offseason? Just interested. You look great atm

Very interesting, I’ve always ran 25mcg year round for years but reconsidering now cause I think it eventually made me gain less than without

hey Hilly, didnt you state that you always use 25mcg t3 along with your 100mcg t4 or are your just using 100mcg t4 standalone right now? just curious

Blood work is really good tbh, wouldn’t change a thing. What else are you using atm

How much t4 are you taking atm

Regarding to thyroid I’d check bloods again in a few weeks, if t4+t4 are still low, I’d use replacement, likely 100t4+ the amount of t3 that brings you to High-Normal levels, likely between 15-35mcg. You look great btw, what was your cycle before show?

Did you try the 175t4/ 10 t3? Did it make any difference for you?

dont know your caloric requirements, body height etc mate, so its hard to judge. With that cycle before, cals seem a bit low to me though

I don’t track macros atm cause I’m not focused on bb atm, just cruising on 175 test e and training for fun. In general, if you’re prone to hypothyroidism, you should always have sufficient carbs to aid t4 -> t3 conversion. How much that is, depends on your personal caloric needs. If you ain’t getting enough carbs, you might start… Read more

Possible, but there’s only one way to find out unfortunately, that’s trial and error. I’d do the 175t4/ 10t3 and see.

I don’t think so, never heard of that before

Tell me how it’s going after a few weeks I’m interested for myself 👍

If i read your bloods correctly you have aft4 of 10 with a range of 9-19, which seems low.

People feel different on different ratios of t4/3, with 150/20 youre taking a ratio of 7.5 t4/t3. Studies found a mean ratio of 15 for t4/t3 ratio in humans, with individuals having a higher or lower ratio.

You could try a different approach like…

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i think t3 doesnt make you flat as long as you need it. But theres much controversy about it. Some higher caliber BB’s implement t3 for their bulking cycles and like it, others say it just makes you flat and weak. Maybe its very individual, idk.

Do you split dose your t3? I normally use 10mcg at 3am, 5mcg at 10.30 and 5 mcg at 6pm.

Im on the exact same dose of t4+t3 as you, 150/20. I dont feel like it has an impact on fullness or my ability to gain muscle tbh, i just use 175mg test e for cruise atm and dont really feel flat if i eat enough carbs.

When cutting, i always get cold hand/feet easily, but with enough carbs, this goes away pretty quick. Are you using any roids…

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Yeah you’re right. Keep us updated

with ft3 testingy the timing is going to matter a lot because of the short half life of t3 meds. i guess youre taking the t3 at morning. if youd draw blood an hour or two later, your ft3 will showup high most likely.

With taking t3 once a day, its like using test prop. Shortly after = high blood levels, lower in the evening. You might benefit…

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could be from the correlation between androgens and TBG (thyroid binding globulin) as youre using primo atm, which is basically adding androgens to your endocrine system that dont aromatize like test would. Thath mechanism could lower TBG, leaving you with more free t4/t3.

That could be the reason behind your higher t4, but as long as you…

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ft3 fluctuates quiete a bit throughout the day in my experience, ft4 doesnt normally. strange

did you change your thyroid replacement? your ft4 came up somehow

Are you taking any thyroid meds atm? Do you suffer from feeling cold /bad digestion /brain fog?

If not, i wouldnt start them with your t4 &t3 levels. Theres plenty of t4 and t3 fluctuates heavily throughout the day.

My labs are

TSH 0.52

fT4 1.5 ng/dl ( 0.9 -1.8)

fT3 3.6pg/ml (2.0 -4.0)

I feel okay most of the time, sometimes i think my metabolism could be faster.

Do you think I would benefit from running t4 lower and t3 a bit higher? I recently read that Jordan Peters for example runs 100mcg t4 +37.5 t3 all the time.

Hey mates,

I need to stay on thyroid meds year round for my hashimotos. Normally I use something like 175mcg t4 + 15mcg t3.

I wonder if it would be better to drop t4 a bit and raise t3 to 25-35mcg.

I’ve heard of people using high doses of t3 year round and with bulking cycles and I’ve heard others say that it’s gonna ruin muscle… Read more

Hey Jordan,

Now that you’ve cut your dosages, did you change anything in regards to your thyroid replacement or do you stay on the 100t4/37.5 t3?

All the best for you✌️

How’s your TSH and ft3? Do you take the 200t4+30t3 all at once?