[andrew]

Sorry I also found this and forgot to mention it,

‘The recent discovery of a specific receptor for Sex Hormone Binding Globulin (SHBG-R) located on the membrane surface of steroid responsive body cells also suggests a much more complicated role for this protein than solely hormone transport’. Williams LLwelyn Anabolics 10th edition

So as you can see it’s a complicated story (pharmacologically) and I am of the opinion as I am sure you are it would be best to collate some data from blood tests to illustrate its potential to act as an AI.

Thanks – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Hi Hilly,

Thanks for your reply, and I appreciate the feedback mate, I shall continue to write posts and add any possible information I have where needed

TBH I am just coming onto forums and open platforms again. After a 7 year layoff I started training again mid last year, but due to the coronavirus, things have slipped off a little. However, in my off time ironically I have spent even more time in gyms, continued academic reading and speaking to people about similar things to this on a daily basis. So to cut a long story short I have not cycled myself in a while, and from my previous cycles/B&C’s/those I have helped, unfortunately I do not have bloods show its efficacy as an anti-estrogen. (This something now I am very keen to do)

Again when it comes to controlled studies to say the evidence base is sparse would be an understatement. So why recommend it you might ask?

However lets have a little geeky conversation like you mentioned ???? (Unfortunately I have got a deadline for some a piece of academic material in entirely unrelated subject, therefore my explanation may appear a little stunted and not in depth. As soon as I have the time I shall read the necessary material and get a definitive answer).

Anyway, so Proviron is 5-alpha reduced, therefore it cannot convert to e2. Now proviron has a much greater affinity towards the aromatase enzyme than testosterone (test that would then aromatise to e2). Proviron is an aromatise enzyme antagonist, and that’s as far as the story goes in ‘mainstream’ forms of material eg. William Llweylns Anabolics

But why does it do this? What is this assumption based upon? (without doing the exact pharmacology texts), I think all its properties are interlinked. It is a shitty anabolic because in muscle tissue it rapidly becomes in active (to diol metabolites) where its binds quickly to the 3-hydroxysteriod dehydrogenase enzyme(3Bhsd). But not only does it interact with this enzyme but also SHBG (giving an increase in free test) and the aromatise enzyme.

Mesterolone could be used ‘to block or denature the endogenous binding protein’, stated verbatim from Steroid Analysis 1995 1st edition.

So there is some information out there I just need to dig, and when I pull the trigger on gear get regular bloods, I don’t currently have access to some people bloodwork that may show its AI capacity.

Another avenue of research is Estrogen dependant female breast carcinoma and treated with masteron . Unfortunately I don’t have the time and capacity at this moment to provide you with a solid answer that’s why I have tried to at some point elucidate a mechanism of action.

Sorry for the rant, hope it is of some help

Regard – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Powerlifting indeed, potentially fighting sport. We all know of the arousal curve, but some people when it comes to the deadlift (the final lift in a full powerlifting meet), after 3 max squats, 3 benches, say with equipment too you’re CNS is fried you’re knackered, and you gotta pull a great deadlift to get a great total, Enter 0.15/0.3mg pens of epinephrine. It’s not common though, we are talking the extreme end. I would imagine that’s why you see it on those sites.

Regards -Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Andrew Jill wrote:

Hi Henry, I presume you taking it to reduce BG, because of GH and/or slin causing raised BG ? I also presume you are using lantus, as although uncommon levermir can vision/eye problems ?Regards – Andrew

Would you split the lantus am and pm?

Hi Brandon,
(This is an edit if you saw my first one which was up for a few mins, and then realised my errors)
I think the use of basal insulin should just be AM OR PM at least initially, not both.
An argument for AM – as there is no (sharp) peak and on paper is active at relatively stable levels for around 24 hours (on paper, individual differences obviously occur) many may disagree, It seems intuitive for AM as you have a day of meals ahead of the shot as the onset is 1-2 hours
PM- However as can be seen in the attached picture, the bulk of its activity is 8hrs onwards, so before bed, a shot would increase around the 6-8hr mark, so most of its activity would be the next day. However it’s onset is 1-2 hours/although the onset is not a peak, this is why it can be a little complicated. Please be careful !
I have attached a picture of novolog to provide some comparison
The reason for using it has some impact, unless you have diagnosable type 2 diabetes – and if this is caused by GH/Fast slin use this should be assessed before using basal AM/PM, OR twice daily, you are risking blunting your natural response to glucose, but that’s just my opinion
Obviously, so many factors influence insulin use and body weight and insulin sensitivity etc
If I were to know you I would discuss at length these individual measures, but generally I would say AM OR PM, not both initially
If you have any further question please ask
Hope this helps
Regards – Andrew
Reference. William LLewylns Anabolics 10th edition[/quote]
Why would you initially not split it?[/quote]
Depends on why you are taking it?

To control raised fasting BG because GH/Slin is resulting in raised fasting BG, glucose intolerance, and to keep running GH/Slin you are adding long-acting to reduce BG levels?

OR

In an attempt to drive nutrients on a constant basis? Not that this works for too long, but I see the reasoning

Twice daily dosing is completely 24 hours insulin, at this point you are replacing an awful lot of the pancreas job, not good in the long run, when pushing things for relatively short amount of time I can see the trade-off, but for a sustained period of time IMO you are risking long term pancreatic negative feedback

It’s something that must be thought out very carefully due to the associated risk , at this point you have other options over long slin that’s if you are using for the 1 of 2 reasons I mentioned, such as GDA’s/Metformin, or novorapid multiple times a day, but that’s just briefly writing something up. Many people use it for different reasons, I’m just giving examples.You may be using it for a different reason.

If you think you need help, please tell me why/if you intend to use and then I can be exact with my recommendations

Hope this helps. These ideas are just my opinion and I am open to discussion

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

I do find it crazy that bodybuilders get such a bad rep about steroids and shit when you see ZERO negative comments on powerlifters using AAS when they in comparison use a lot more than bodybuilders do… and there sport is widely streamed on top sports channels and everything but you never hear them talk negatively… makes no sense…

Yeah I agree, rarely do people speak of gear when the worlds strongest man is on TV. I think its because of the sheer look of bodybuilders, you see Markus Rhul and people have no relatability – and try to diminish their achievement by saying its all drugs. Whereas most people think strongmen are like some big fat fella that stands on night club door (ironically possibly using steroids too) such as Glenn Ross.

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Andrew Jill wrote:

Hi Henry, I presume you taking it to reduce BG, because of GH and/or slin causing raised BG ? I also presume you are using lantus, as although uncommon levermir can vision/eye problems ?Regards – Andrew

Would you split the lantus am and pm?

Hi Brandon,

(This is an edit if you saw my first one which was up for a few mins, and then realised my errors)

I think the use of basal insulin should just be AM OR PM at least initially, not both.

An argument for AM – as there is no (sharp) peak and on paper is active at relatively stable levels for around 24 hours (on paper, individual differences obviously occur) many may disagree, It seems intuitive for AM as you have a day of meals ahead of the shot as the onset is 1-2 hours

PM- However as can be seen in the attached picture, the bulk of its activity is 8hrs onwards, so before bed, a shot would increase around the 6-8hr mark, so most of its activity would be the next day. However it’s onset is 1-2 hours/although the onset is not a peak, this is why it can be a little complicated. Please be careful !

I have attached a picture of novolog to provide some comparison

The reason for using it has some impact, unless you have diagnosable type 2 diabetes – and if this is caused by GH/Fast slin use this should be assessed before using basal AM/PM, OR twice daily, you are risking blunting your natural response to glucose, but that’s just my opinion

Obviously, so many factors influence insulin use and body weight and insulin sensitivity etc

If I were to know you I would discuss at length these individual measures, but generally I would say AM OR PM, not both initially

If you have any further question please ask

Hope this helps

Regards – Andrew

Reference. William LLewylns Anabolics 10th edition

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Both of those books are excellent reading, an excellent foundation.

I have many I could recommend, but you need to break your reading up into sections for which I can recommend some books/articles, or else I would just have to write a long list of books some of which could be very specific.

Broadly speaking to mention a few I can think of now, but far from an exhaustive list

Arnold Schwarzenegger’s Encyclopaedia of bodybuilding. Absolute classic, covers so many exercises.

Dr Scot Stevenson – How to be your own bodybuilding coach, fantastic, really dense in useful knowledge

Kelly Starett – Becoming a supple leopard – fantastic for mobility

Dr Mike Israetel – How much should I train ?

Dr Mike again – Recovering from training ?

Justin Harris- Comprehensive nutrient 1&2

John Little – The wisdom of Mike Mentzer & High intensity training

Brad Schoenfield – Science and development of muscular hypertrophy

Josh Bryan – Built to the hilt

If you interested in the supplement/ PED I can recommend a whole category of other books

I could recommend many which focus the development of a successful mindset and psychology

Please let me know any specific areas in bodybuilding, where you feel you lack knowledge I may know a book that may help. I have suggested a few, all of which I have read and highly recommend.

Please let me know if you have an questions, I have attached a few pictures of the suggested books

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Hi David,

Looks good, what about the addition of Proviron, increases free testosterone, should prevent the need for an AI and can have the added benefit of an increased sex drive.

IMO it’s main benefit is that it negates the use of AI’s, so wouldn’t need to use adex

Hope this helps

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Hi Henry, 

I presume you taking it to reduce BG, because of GH and/or slin causing raised BG ? 

I also presume you are using lantus, as although uncommon levermir can vision/eye problems ?

Regards – Andrew 

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Yeah agree Hilly. Attached a photo of Eddie, now I respect this man an awful lot for his achievements, when he was at his max (around the deadlift and worlds win)I was thinking o man don’t die, you can see an awful video where he nails the deadlift drops to the floor the camera is on his poor missus who looks completely helpless and devastated , in his book he talks about a situation when he over dosed on potassium and it almost killed him.
I must add all these guys I have nothing but admiration and respect for their achievements in their chosen sport, we are merely discussing the health implications of such choices, this does not deduct from their success
I added a picture of Scot Mendleson, held the raw bench at 715lb for probably 20 years and the equipped lift. In a podcasts he admitted to using 20 anadrol a day before a comp, that’s 1 gram of oxymetholone a day, only know what this did to his organs
The other picture is of Donnie Thompson, the first man to total 3000lb total, he like many powerlifters in the picture exemplifies ‘that’ look I think Hilly was referring to
Much of this was done pre-internet, complete lack of education, the demopressin and ephedrine was an old school powerlifter I have too much respect to name, but his discussion on these topics is in the public domain, the ephedrine one is about when you had got all you powerlifting gear (mainly squat suit) and had an ‘ephedrine piss’ whereby you couldn’t genuinely tell if you needed a piss or it was too much ephedrine stimulating the response, and should you remove your equipment or not . Epinephrine injection is another ‘ relatively common’ amongst the crazies in the powerlifting too.
Too much madness to list
We have a good thread here with benefits of testosterone over other anabolic , IGF and tren and finally powerlifting madness
Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Holy fuck that’s a lot… wow… I was thinking extreme but god damn that is next level fucing extreme…. I would love to see his blood work after the lift… I could only assume everything would be absolutely sky high and near death levels!?

I doubt near death. Drugs can be taken to offset liver enzymes, but that’s the least concern, liver is a very robust organ, not saying that it should be abused. Lipids would be shot to shit, he would need to drop to trt, clean his diet up, plenty of cardio, health supps and potentially statins if necessary. Blood drawn off to remove the excess red cells. The main thing is blood pressure and the kidney risk. blood pressure throughout the training cycle must be controlled, possibly an ACE inhibitor like lisinopril. When it comes to the lift they ain’t not controlling blood pressure , gotta cross your fingers and hope for the best. He will be fine to fight another day.

Hope this helps.

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

@andrewjill after comparing test to tren, how would you compare npp / deca (nandrolone ) to tren on a mg to mg basis

Again it’s very difficult to compare, like apples and oranges, but I would say they are equal, however IMO nandrolone can be pushed further as it doesn’t drive you insane, there is a cut point for tren where more equals greater sides – as with any compound but you pay for it far more with tren, and IMO Tren is for precontest or powerlifting peaking, outside of that you can use other things to achieve equal anabolism without destroying your mind, but that’s just me, I have know powerlifters run 200mg tren ace a day when peaking and come out the other end fine, I know I wouldn’t
Hope this helps , any questions fire away
Regards – Andrew [/quote]
Awesome feedback! Thank you! I personally love npp is the offseason / gaining phase and tried tren for the first time last prep and was absolutely insane… strength went through the fuckin roof while dropping cals and doing shit tones of cardio…
Since you brought up powerlifting… what do you think Thor would have been taking for his peak on that 501kg deadlift the other day? Tren, halo? Just curious [/quote]
Yeah tren can be magic,but also a devil, some suffer no side effects, and for those then they can use it for blasts, but like I said IMO it should be used for a specific purpose, that’s how I would use it and that’s the advice I would give to anyone I care about

I have a few points to preface to this discussion;

*So talking of some peaking for a max deadlift, you obviously have the years of cycling/ B&C like a bodybuilder in the years/ decades before the Olympia/Universe to build up such an incredible strength base.

*You have to consider body weight, at 205kg the sheer muscular weight his frame carries.

*An individual could also spend years and years heavy blast and cruise, and then when they may have a period of lower doses can return to moderate use, what I mean is just because it’s his maximum deadlift does not necessarily mean it’s his max cycle, although it could well be.

*Also the fact there is dramatic differences in use across all competitive endeavours

*I wouldn’t normally be asked about something like this and give dosages of such magnitude, but it’s a closed forum so I feel comfortable.

*The suggested dosages are no more than an intellectual estimation

That being said:

16 weeks out

Testosterone Base could be anything from 500mg to multiples grams, I would say 1500mg

Equipoise at a dose that provides huge appetite and stamina/endurance for long training sessions (especially when it comes to equipment like deadlift suits comes into play) 500mg up to 1500mg, possibility 1000mg-1200mg

NPP/Deca, for joint support, 400mg -1500mg, around 1000mg

GH and insulin,whatever is required to recover sufficiently from training. GH 5-12iu, lets say 10iu. Insulin is anyone’s guess, could be none and he has never used it, could be 100iu a day.

If tren doesn’t send him crazy or fuck his digestion the tren e/h @ 800-1200mg

That could be it at this point, it’s all about hitting the numbers and recovering, and digesting the amount of food required to support this.

If orals don’t affect appetite and digestion, anavar up to 150mg, oxymetholone up to 300mg, dianabol up to 100mg , rotating them, or combine if he’s willing to risk until the end

6 weeks out

Some may choose to lower Deca, already built up significant levels and supported joints

More testosterone, 150mg testosterone suspension a day
Pre workout Andro’s; 2mg Methyltrienolone, Mibolerone (cheque drops), tren suspension, any one of those or a combination
CNS stims: ephedrine
Orals: Anavar , and dianabol or oxymetholone (or both) if not running before, or continue to run if already was

4 weeks out

Halotestin up to 50mg ed

2 weeks out

200mg of tren ace / 300mg of oxy pd

A few days before

Potentially the use of a drug called Desmopressin, essentially an anti-diuretic, causes maximum water retention and bloat to force yourself into the suit. This technique is less used with deadlift equipment as its least effective in this lift, most effective in the squat and bench.

On the day

Which ever preworkout androgen have worked most effective, plus stims such as ephedrine

And that’s the max I would think
Could have been 450 test e 450 tren e , 50mg anavar and 25 Halo, and all the above complete unknown madness, I just wanted to give you an example of the possible extreme option.

Well you could take it a step further

Now I personally don’t think Thor would venture into this end, and dare I say over the top 🙂 I have added a few pictures for your viewing, nasal cheque drops spray, IM/IV ephedrine, and a test/tren/methyltren/oxy/halo preworkout injectable cocktail.At this extreme end anything can be justified, painkillers are unfortunately common, but I don’t think this thread needs some real extremes.

Hope that may have given you some insight into how crazy thing can get

Regards- Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

@andrewjill after comparing test to tren, how would you compare npp / deca (nandrolone ) to tren on a mg to mg basis

Again it’s very difficult to compare, like apples and oranges, but I would say they are equal, however IMO nandrolone can be pushed further as it doesn’t drive you insane, there is a cut point for tren where more equals greater sides – as with any compound but you pay for it far more with tren, and IMO Tren is for precontest or powerlifting peaking, outside of that you can use other things to achieve equal anabolism without destroying your mind, but that’s just me, I have know powerlifters run 200mg tren ace a day when peaking and come out the other end fine, I know I wouldn’t

Hope this helps , any questions fire away

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Anadrol would kill my appetite and give me headaches, neither conducive to long term gains. However, it’s very exceptional for strength, so at times a would use it preworkout when strength was a priority. The thai anadrolics or Iranian anapolan are great.

Dianabol is a totally different story, one of my favourites. No side effects for me, maybe some water retention, managed by diet, but not really a side effect for me as it maximises strength. In my younger years I experimented quite a bit with dianabol and it worked fantastic. I remember having a combination of 100mg test prop 100 NPP 50mg injectable dianabol per ml and using 2ml eod on a rebound (totally unnecessary I know) and size and strength was unparalleled. Another trial was the Pharma napoism, now these are dynamite, I tried 50mg of those with 450 mg of tren and I remember thinking ( quite funny now looking back ) ‘am just going to carry on get stronger and stronger indefinitely ‘ 🙂 . If you can get legit napoism’s then your golden

Now we have sites like this where we can share information there is no need to ever engage in the madness I tried above and I certainly do not advocate such dosages, I was my own human Guinea pig.

Anyway to directly answer your question, for me personally dianabol can be used and facilitate strength/size gains in the long run, as I can eat, for me anadrol has one purpose and that’s peaking strength

Regards – Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

I find it very hard to read books with my dyslexia, so I tend to listen to videos on YouTube or I’m going through the educational series that Jordon has done atm which is helping me a lot and I’m finding it very interesting ????

_________________________________________

Jadekelsie

Certainly is great. I definitely recommend audible, 7.99 a month for a book, almost all the main titles on amazon, including very good bodybuilding related ones, 2 which I have attached, would highly recommend them as a books and in audio format. Audio books are great for cardio
Andrew [/quote]
Thank you I will have a look at them definitely ????

_________________________________________

Jadekelsie

[/quote]
The first month is free so you could get any of those books and try it audible, which is great tbh. sync’s your place between devices etc

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.