[andrew]

This drug was stopped in Phase I clinical trials due to cancer in rats. However, it is a little more complicated than that as the dosage administered to rats was generally far greater than what a human would consume. This is the scientific literature we have available. But we speak freely of the actions of let’s say Nandrolone, it’s well understood on a pharmacological and anecdotal basis, but not in the scientific literature in supraphysiological dosages, so we have to weigh up these judgements and decide if its a risk worth taking.

I have found it to have a profound effect on cardiovascular capacity, however this was when I was entirely detrained for years, and from what I have seen anecdotally broadly speaking the closer someone to being detrained the greater the benefit. This however does not mean it does not have merit in those on the heavier side who is athletic, for more enduring sets or workouts which require a great cardiovascular capacity, then it may be helpful.

Injection? Why it’s orally bioavailable. You could surmise it has similar effects but this is not necessarily the truth. ‘Companies’ always want to expand their market and IMO that’s what happens with injectable Cardarine/GW1516. China has recently banned this, not that really matterS, we still get fentanyl ok so I’m sure Cardarine will get through, but injecting it taking it another step, I have seen this injectable sr9009. So why double down on an already risky trade-off is just asking for trouble IMO. I can safely say its effects are unquantifiable. 99.99% of successful bodybuilders would have no idea what this is. We are on the fringes of potential PED pharmacology here and that’s saying something.

Sorry for the rant, but yeah not worth it IMO, try the oral, run it for short cycles if it helps, but stick to the nuts and bolts of what is tried and tested.

Any further question please ask away

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

It’s done now, but I wouldn’t touch AIs after crashed e2 unless my tits were screaming stop or I had a test that was high, you want unbound aromatase to build up in the system, good thing is when you stop arimidex it’s action is nullified unlike aromasin (this can be good or bad depending on the situation, and aromasin has a slightly less detrimental affects on lipids, but that’s minor right now,don’t worry about that decision yet).

EQ aromatises at 50%the rate of test, it’s a testosterone derivative, some argue it reduces partially into a metabolite which is helpful re e2, but I am yet to see it and I doubt it’s strong enough to outweigh the e2 of 50%, ergo EQ for e2 is shit IMO. EQ adds mild anabolism and ravenous hunger in some, that’s why assumed you were using for the hunger needed to keep the meals coming. Masteron is far better for managing e2.

Keep getting your BP done, get bloods and consider EQ option

Regards

Andrew

It’s very strange, some forums I’ve seen countless bloodwork showing additional EQ has completely crashed the estrogen. Seems to be very person dependant though. I do feel dry (bar the water retention I gain during the day from GH and slin) so I imagine it’s gone low. I’ll get this tested to confirm.

Blood sugar has been fine, 4.6 waking and after my burgers last night I was within the range my weights been sitting at so I have increased the carbs in my diet by 75, and added a small amount of fats in meal 1 in the form of peanut butter. Still think my calories are low considering I dieted on this before however I’ll monitor for a few days and reassess.

Yeah I have seen some case reports, I have just thought other things have been at play, but like you said it really is person dependant.

Its just about slow incremental changes regarding water balance, if someone came to me (theoretically obviously) and asked how could I retain as much water as quickly as possible? You would dehydrate-crush e2, then use test and another aromatising compound on top with GH and long insulin, that’s the perfect storm, but I can understand transitioning to this phase of development, your body is primed for hypertrophy, but you need to get the most from the least, you want the scale to creep up, obviously some post-show water is expected. You get my point.

Are you using pharma GH? and do you compete in open/classic/physique?

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

It’s done now, but I wouldn’t touch AIs after crashed e2 unless my tits were screaming stop or I had a test that was high, you want unbound aromatase to build up in the system, good thing is when you stop arimidex it’s action is nullified unlike aromasin (this can be good or bad depending on the situation, and aromasin has a slightly less detrimental affects on lipids, but that’s minor right now,don’t worry about that decision yet).

EQ aromatises at 50%the rate of test, it’s a testosterone derivative, some argue it reduces partially into a metabolite which is helpful re e2, but I am yet to see it and I doubt it’s strong enough to outweigh the e2 of 50%, ergo EQ for e2 is shit IMO. EQ adds mild anabolism and ravenous hunger in some, that’s why assumed you were using for the hunger needed to keep the meals coming. Masteron is far better for managing e2.

Keep getting your BP done, get bloods and consider EQ option

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Not a problem, sounds like you are in a good position to push up, but a few things should be noted. Blood work would be ideal, I would advise e2 management via proviron/masteron personally to avoid lipid damage, get it at the top end of the range, if you have gyno issues use tamoxifen. I mentioned previously that I think you should optimise insulin sensitivity on off days with the use of a GDA-Berberine/ALA/Chromium etc and/or Metformin.

Fantastic that you write everything down, IMO this is very important in understanding what works for you personally and to formulate continued progression.

Water retention after a period of dehydration is common for obvious reasons. Literally carbs/test/slin/gh/sodium ALL heavily influence water balance alone. You have not had any issues with feeling breathless? Tight chest? Do you monitor blood pressure? Have you got deep sock marks? Blood volume has just dramatically increased, so continuous water intake (NOT distilled water)will help alleviate water retention.

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Right ok, IMO if you are first time user of GH and on the rebound of a show I would again advise against its use at this point, I am providing information to keep you safe, you are completely entirely entitled to do what you want with your body-that is your right, you don’t know me personally but I shall present the evidence/science to mitigate any potential harm.

So lets deal with water, you are post show, 1 gram of carb =3g of water, sodium x grams=50x of water, at baseline, you have test/e2/gh/slin all of which in their own right result in increased mineral retention = ++++water, essentially due to the function of aldosterone, the effects/side effects become less apparent with a consistent dosing schedule=stable blood concentrations and as such could be reduced as things ‘even out’, mineral (sodium/potassium) intake would depend on what you did for your show, how long ago its was etc all these things are very individualistic so if you are not clued up on the chemistry many people have coaches, but its certainly good to ask questions and you are in the right place, you just need to make considered/quantifiable changes that you can sustain indefinitely-rather drastic changes, again that is just my opinion

Regarding Lantus, most used as the run high gh+high carbs=high BG, reduce this with Basal insulin that does not peak, some people run it the day after training in an attempt to maximize that recovery period-Regarding fats it depends on current diet/leanness/response to carbs, fats could/should be lower, and when using short insulin it’s easy to not eat fats for that short window, with long I would base it off the results on muscular/fat gain ratio, fat should be low, but sources of monosaturated/’healthy’ fat, when combined with low GI carbs, can reduce the glycemic loads of the meals=stable blood sugar. You might do well off really low fat on those days, it’s a balance,a fine balance and you need to record what you are doing to avoid mistakes and note what works, or you need a coach.

Honestly, if you have just added GH for the first time, just let it settle with a nice e2 level should give you some nice IGF readings, but if you do consider it, these are some (certainly not all) things you may want to consider when planning.

Hope I have been of some help, please take care my friend

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

1st things first before I reply, get your blood tested multiple times, check strips and all associated stuff is in date, this reading is very spurious, do you have any signs of hypo? Sweating, tired-yawning, sick, but voracious hunger etc, if in any doubt just slam some fast carbs for the sake of life/health and then check it again in 15/30/45 mins, might need a new monitor. Do you have an average waking reading?

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Or did you mean insulin protocol wise on off days, if so I would advise a good GDA and/metformin on those days to try and maintain insulin sensitivity , get your HbA1C done every 6 weeks at least in the beginning, and morning and post workout blood sugar

I realise now I misread what you was asking but hopefully this shall cover some of it, I shall rewrite anything I didn’t cover for you tomorrow brother

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

On rest days I would keep fat intake high, as you using test/EQ you want a nice e2 balance for IGF production/joint health etc is you question about fat amount ? Or source/s.

Its an incorrect assumption that fat needs to be minimal with insulin, as with everything balance is key, people say well insulin will store the fat – this is a very simplistic view, what people overlook is fats when combined with carbohydrates reduces the glycemic load ( not glycemic index of that carb source) of that meal and thus stabilises blood sugar, this is what you want, so fat low yes, but a little can help

Any questions fire away

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

To answer your question in short, yes it can be run, but to what end, now everyone has differing opinions on this and I generally agree with a lot of suggested protocols. But Lantus has no peak and generally is used to reduce high blood glucose (BG)from high GH and high carbs. What could potentially happen as you reverse diet from the show and use long slin is you destroy insulin sensitivity. I think with the amount of juice you are on plus GH, I personally dont see its use right now. Many may disagree, and if they have sufficient justification then by all means it may work, you just dont want to listen to be cavalier and easy add 30iu with lots of carbs and get nothing but fatter, rather the opposite, the efficient partition of nutrients. I would see what others guys have to say and then just start low and keep your BG readings.

Hope this helps

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

If that doesn’t work you could try warming it in a shallow pan of water 1/3 up the vial and heat it steadily, you may need a green(or the biggest you have) pin in the top to equalise any negative pressure. OR put it through a 0.22um filter that fits on a syringe (can buy on eBay). I must stress this is not good practice and does not guarantee sterility, but if you want to experiment on your pet rat you could try this.

Regards

Andrew

https://www.ebay.co.uk/i/114228511120?chn=ps&norover=1&mkevt=1&mkrid=710-134428-41853-0&mkcid=2&itemid=114228511120&targetid=938486033460&device=c&mktype=pla&googleloc=9046360&poi=&campaignid=10199638297&mkgroupid=101938342477&rlsatarget=pla-938486033460&abcId=1145987&merchantid=113430342&gclid=CjwKCAjwrKr8BRB_EiwA7eFapmGG-XZ-oaDyJtp2ZYOuSyX6MTxio3xEF1nIuUbmj4Ex-71WVqI66BoCkawQAvD_BwE

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

Have you ever ran insulin previously?

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

As mentioned incomparable, they can be used for a ‘similar’ clinical outcome- as such with the vast expanse of drugs which fall under Diabetes (typeII).

I would highly recommend the video (which is outstanding) of Dr Dean on AAS Pharmacology, watch it start to finish-make notes and understand its premises, why is this important? (because as Hilly and Matteo said in their own words) There is importance in the understanding of; Pharmacodynamics(PD)- the body’s response to such drugs, Pharmacokinetics(PK)- its movement through the body, and you could associate this with IGF expression. In the understanding of these concepts, you can begin to understand clinical research, which will greatly help you understand how these drugs work.

Having said that, and I not advocating the use of anything, but you can develop a body of research by using these compounds and recording biomarkers or coaching people who do, there are exceptions to this obviously. My point is the individuality of results regarding heavyweight bodybuilders using these compounds varies wildly.

Hope I have been of some help, some fantastic posts from Hilly and Matteo, lads you have me sent down a wormhole, well hey what are Saturday afternoons for if not reading scientific literature of Metformin and IGF/splice variants, much appreciated

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

I use a brita filter mate. Removes chlorine and limescale. Best option is to have a reverse osmosis tank fitted or distill your own water. Hope that helps.

Thanks for the reply mate.I have looked into both, and what concerns me unless my basic understanding of water and mineral content is quite possibly incorrect, that in removal many of the contaminants it’s removes minerals, and as such if you drink distilled water for a prolonged period of time it pulls minerals from your body due to negative gradient.

So do people use reverse osmosis and are covered by multivitamins ?

A lot of the guys on videos on here I have seen using bottled water, but I don’t if that’s just for convenience around workout window etc

If you read this guys please just leave a quick comment on what your considerations are when it comes to water, as it’s something I have wondered about for years, obviously spending a lot on bottled,but done it for convenience and mineral balance ( if in fact that is the case I don’t know).

Thanks guys and girls

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

You are most welcome, life is about self-improvement IMO, success and victory experiences are what we value most as humans, (as well as many other things, social engagements etc)

Sounds like you have some achievements and experiences which will hopefully give you fulfillment in life

I wish you all the best, any questions just ask away

Best wishes

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.

[andrew]

40 is a reasonable dosage, you need a BG monitor, and you dose on this basis, get a journal and keep dose/carb intake with respective to fasting BG/Post workout so you can tailor the dose if you get me

I would recommend if you are on a high carb/high GH for extended period test HbA1C

I would also recommend a GDA protocol/mini-cut/keto periods to try and maintain some natural insulin response, so Metformin/SGLTR inhibitors etc and/or Berberine/ALA, but be careful combing with insulin as these drugs/supplements can obviously potentiate insulin significantly

And it depends or your purpose for use, works well for HbA1C and constant elevated BG, but for growth short insulin protocols could be implemented, but these can be dangerous in combination and you must fully understand how carbs affect BG, and then match the insulin to carb intake-not forcing carbs to keep up with insulin, but that’s just my opinion

I could go on all-day, sorry t0 rant

Hope I have been of some help, if you have any quieries please ask away

Regards

Andrew

Disclaimer: Please note that the information provided in my post is for entertainment purposes only. I would vehemently recommend you always do your own research and entirely understand the ramifications of your actions. Always seek medical advice before you make a choice that will impact your health.