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  • DrDeanStMart

    Member
    August 8, 2019 at 7:49 am in reply to: Blood work

    I replied yesterday but doesnt appear to have saved.

    It would appear what you used was either fake or you got lucky and HPTA restored by itself following the clearout period.

    SHBG can be high for several reasons – insulin resistance, high estrogen, high cortsol etc.
    Very hard to give an exact root cause without figuring it out with more context.

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  • DrDeanStMart

    Member
    August 8, 2019 at 7:46 am in reply to: Interpretation of blood work

    hs-CRP is very elevated at 6 so there’s some source of inflammation which needs addressing and is putting risk of CV disease.

    HDL is low but as an artefact of the elevated testosterone and skewed E2 ratio.
    Rest of lipid panel is relatively normal.

    RBC and liver would appear normal

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  • DrDeanStMart

    Member
    August 7, 2019 at 12:23 pm in reply to: Blood work – High SHBG?

    Potential insulin resistance or elevated cortisol.

    Looks like you were jabbing plain oil if bloods came back no change to baseline bloods or you got very lucky and HPTA recovered perfectly (which can happen)

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  • DrDeanStMart

    Member
    August 6, 2019 at 6:58 pm in reply to: Dr Dean Q&A Thread

    Klaas – I would still probably check E2 before adding Tren and nandrolone wo yiu know baseline value.

    Tren unfortunately can interact in the ELISA assay and give a false elevated E2 result. Its progestin activity can augment the E2 receptor.

    Nandrolone can aromatise but at a very low rate but in theory it should not be detected as estradiol.

    Start low when adding tren or nandrolone so you can closely watch if sides develop

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  • DrDeanStMart

    Member
    August 6, 2019 at 6:54 pm in reply to: Dr Dean Q&A Thread

    Stano – even if diet hasn’t changed there could be an issue. Androgens can also interact with mineralcorticoid receptors to increase Aldosterone which may be happening. I would work TVA as alot of people with distention tend to have weak underlying TVA

    James – I really do not like finasteride at all. The benefits to risk are ust not worth it. I had a thread on hair loss. If you’re genetically susceptible to losing your hair then delaying the inevitable its still going to happen. DHT has a lot of positive effects in the body, one mainly being strength and CNS regulation that removing its formation just for the sake of hair loss is not wise. It is also the primary androgen for sexual function so again I just don’t see the point in the off label use for hair loss.

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  • DrDeanStMart

    Member
    August 6, 2019 at 1:35 pm in reply to: Dr Dean Q&A Thread

    Stano – again need a little more context.

    Does the water retention ever dissipate? Do you train your transverse abdominus?

    Is the distention from a food insensitivity or lack of gut control.
    Did it begin with some change you can remember.
    Have you tried an elimination diet?
    Does breath smell to suspect Small Intestinal Bacterial overgrowth.
    Does faeces smell?

    Rotties – Boswella can be used year round.

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  • DrDeanStMart

    Member
    August 6, 2019 at 11:34 am in reply to: Dr Dean Q&A Thread

    Stano – When you say water retention and bloating what do you mean specifically?

    Morning time, evening time, after eating certain foods (protein, fat, veg), heavy sock band etc…..

    Not giving me much with what you’ve said

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  • DrDeanStMart

    Member
    August 5, 2019 at 9:50 pm in reply to: Dr Dean Q&A Thread

    Neil – I dont really rate Eq tbh. in the grand scheme it is really a poor anabolic.

    Keith – Sure these are all average half lifes as they will differ depending on PDE7B polymorphisms (this is the enzyme which cleaves the ester). Simple rule, the longer the ester the longer the half life

    Below are the most common (Ive left out some.of the fancy ones like Laurate as no one uses them)

    Average half life
    Testosterom Base – 90 mins
    17a methylated orals – 8-9 hours
    Acetate – 1-1.5 days
    Propionate – 1.5-2days
    Phenylpropionate – 2.5-3 days
    Cypionate – 5-7 days
    Enanthate – 5-7 days
    Decanoate – 7-10 days
    Undecyclenate – 10-14 days
    Hexahydrobenzylcarbonate – 10-14 days

    Clear out time in general is 5 half lives so multiply each of the above by 5 to give an average time when fully cleared.

    Its difficult to say – My Bodypower talk will be on the site soon discussing Pharmacology of AAS. Ideally daily injections regardless of ester will yield stable plasma levels. Fast acting esters have the potential to clear faster but again also require more frequent injection

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  • DrDeanStMart

    Member
    August 5, 2019 at 11:38 am in reply to: Blood Results interpretation please

    Values are as expected for training.

    Lipids are skewed from oral use. Hard to give a timeframe when that will normalise. HDL is normal but LDL synthesis is elevated which could be diet related also

    Liver is still recovering from oral use also

    Watch for symptoms of high estrogen and obvisouly address as needed.

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  • DrDeanStMart

    Member
    August 5, 2019 at 11:32 am in reply to: Insulin injection

    And also do not do insulin intramuscularly

    You will not have control over its absorption and may prolong its effect

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  • DrDeanStMart

    Member
    August 5, 2019 at 11:32 am in reply to: Insulin injection

    Way too big

    Yellow 31g but I would get correct pin attachment for pen.

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  • DrDeanStMart

    Member
    August 5, 2019 at 10:42 am in reply to: modafinil – 50mg dose

    I would not use it long term at all as it will mess up acetylcholine levels in the long run and is what will cause the withdrawal and headache.

    50mg is a nice dose to start to yield appreciable increases in focus when combined with Caffine and a choline source like Alpha GPC.

    As with everything, a low dose to begin would have been preferred then adjust from there.

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  • Lipid panel here is not too bad all things considered.

    Cardarine has been shown to have positive effects on keeping hepatic lipase low. If you watch my highlight on IG I breakdown any concern surrounding its potential carcinogenicity.

    Its a very useful tool also for aiding PPAR expression as well as aerobic capacity.

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  • DrDeanStMart

    Member
    August 5, 2019 at 10:35 am in reply to: Dr Dean Q&A Thread

    Wow – amazing response guys 🙂

    Rotties – I would in that instance look at taking them in the late evening then? What about looking to add Boswella as a COX inhibitor daily? Would be beneficial in this instance.

    Tyler – More than likely the Ashwagandha. People respond so differently to adaptogens both positively and negatively from a hormonal perspective.

    Joany – Just take them in the evening time.

    Borja – that is a very difficult question answer as regardless of B&C or Cycle/PCT the HPTA will be shutdown and FSH production effected knocking onto sperm production. Unfortunately that would have to be a decision on your part but either way as I said sperm production will be effected regardless. Neither of the two I can say will be better from a fertility standpoint and maintaining sperm production.
    A full PCT post use regardless will always yield positive effects on fertility providing the HPTA responds to output FSH again. Otherwise synthetic forms of FSH (hMG) would need to be considered. If you read through my full log as well as the commments I put in Ryan’s there’s more there for you to consider.

    Neil – Its most likely due to the progestin acitivity of NPP interacting at the E2 receptor. I would stop the NPP and also assess E2 in bloodwork to make sure it is not elevated.

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  • DrDeanStMart

    Member
    August 5, 2019 at 10:26 am in reply to: Blood Results interpretation please

    Can you give more context please?

    Compounds being taken?

    Did you train the day before?

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